To provide a medical device, whereby the non-specific absorption amount is reduced, its durability is excellent and eluents from the surface layer are reduced. The medical device comprises a device substrate and a surface layer provided on at least part of the surface of the device substrate in contact with water, wherein at least part of the surface of the device substrate is made of an inorganic material, the surface layer is made of a cured product of a compound having a biocompatible group and an alkoxysilyl group, the content of the biocompatible group in the compound is from 25 to 83% by mass, and the content of the alkoxysilyl group is from 2 to 70% by mass.