Clamp designs and methods relating thereto for working on one or more of workpieces are described. An exemplar clamp design includes a unitary u-shaped frame having a bight portion flanked by multiple jaw portions, all of which are designed to secure one or more workpieces (e.g., cabinet face frame). The u-shaped frame, at any of its portions, has disposed thereon at least one work window that provides access to one or more secured workpieces. Further, one exemplar clamp design provides a work guide element rotatably coupled to the u-shaped frame, disposed adjacent to the work window, and having defined therein a guide aperture. In, one rotated, work position of the work guide, the guide aperture allows a tool to access and/or work, through the guide aperture and the work window, on a desired location on the workpiece.