Invention Grant
- Patent Title: Binding molecules
-
Application No.: US18405910Application Date: 2024-01-05
-
Publication No.: US12134647B2Publication Date: 2024-11-05
- Inventor: Jakub Jaworski , Kate Atkin , Arnaud Techine , Vijaykumar Karuppiah , Florence Schlosser , Ana Pereira Ribeiro , Chandramouli Chillakuri , Nathaniel Liddy , Andrew Creese , Martin Ebner
- Applicant: Immunocore Limited
- Applicant Address: GB Oxon
- Assignee: Immunocore Limited
- Current Assignee: Immunocore Limited
- Current Assignee Address: GB Oxon
- Agency: MEDLER FERRO WOODHOUSE & MILLS PLLC
- Priority: GB2300227 20230106
- Main IPC: C07K16/00
- IPC: C07K16/00 ; A61P35/00 ; C07K16/28
Abstract:
The present invention relates to binding molecules that comprise T cell receptor (TCR) variable domains and which can bind to a PRAME peptide-HLA complex. In particular, the present invention relates to binding molecules that bind to PYLGQMINL (SEQ ID NO: 1) in complex with HLA-A24. The invention also relates to the use of such molecules for the treatment of malignant diseases.
Public/Granted literature
- US20240228617A1 BINDING MOLECULES Public/Granted day:2024-07-11
Information query
