Invention Grant
- Patent Title: Structural domains of antisense RNA molecules up-regulating translation
-
Application No.: US16967254Application Date: 2019-02-05
-
Publication No.: US12134768B2Publication Date: 2024-11-05
- Inventor: Stefano Gustincich , Silvia Zucchelli , Peter Podbevsek , Janez Plavec , Piero Carninci , Hazuki Takahashi , Toshio Yamazaki , Takako Ohyama , Harshita Sharma
- Applicant: Fondazione Istituto Italiano Di Tecnologia
- Applicant Address: IT Genoa
- Assignee: Fondazione Istituto Italiano Di Tecnologia
- Current Assignee: Fondazione Istituto Italiano Di Tecnologia
- Current Assignee Address: IT Genoa
- Agency: McAndrews, Held & Malloy, Ltd.
- Priority: IT102018000002411 20180205
- International Application: PCT/IB2019/050914 WO 20190205
- International Announcement: WO2019/150346 WO 20190808
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C12N15/67 ; C12Q1/68

Abstract:
There are disclosed functional nucleic acid molecules comprising a target binding sequence comprising a sequence reverse complementary to a target mRNA sequence for which protein translation is to be enhanced; and a regulatory sequence having two-dimensional structures comprising specific stem-loop and internal loop domains and displaying translation enhancing efficiency.
Public/Granted literature
- US20210139898A1 STRUCTURAL DOMAINS OF ANTISENSE RNA MOLECULES UP-REGULATING TRANSLATION Public/Granted day:2021-05-13
Information query
IPC分类: