Invention Grant
- Patent Title: Fusion imaging gene and lentiviral expression plasmid, lentivirus, cell, preparation methods and applications thereof
-
Application No.: US18430589Application Date: 2024-02-01
-
Publication No.: US12134837B2Publication Date: 2024-11-05
- Inventor: Zhiqiang Liu , Zengqiang Yuan , Cui Wang , Xiaowen Xing , Bingshui Xiu , Shihong Liu
- Applicant: ACADEMY OF MILITARY MEDICAL SCIENCES, ACADEMY OF MILITARY SCIENCES OF CHINESE PLA , BEIJING JIUYU ONCOLGY CO., LTD.
- Applicant Address: CN Beijing; CN Beijing
- Assignee: ACADEMY OF MILITARY MEDICAL SCIENCES, ACADEMY OF MILITARY SCIENCES OF CHINESE PLA,BEIJING JIUYU ONCOLGY CO., LTD.
- Current Assignee: ACADEMY OF MILITARY MEDICAL SCIENCES, ACADEMY OF MILITARY SCIENCES OF CHINESE PLA,BEIJING JIUYU ONCOLGY CO., LTD.
- Current Assignee Address: CN Beijing; CN Beijing
- Agency: Pilloff Passino & Cosenza, LLP Rachel Pilloff
- Agent Sean Passino
- Priority: CN202110882190.4 20210802
- Main IPC: C40B40/08
- IPC: C40B40/08 ; C12N15/10 ; C12N15/65 ; C12N15/86
Abstract:
A fusion imaging gene and lentiviral expression plasmid, lentivirus and cell, and preparation methods and applications thereof are provided. The fusion imaging gene includes bioluminescence imaging gene, fluorescent protein gene and calcium imaging gene. The three genes are linked by linkers. The fusion gene is inserted into a modified lentiviral expression plasmid to obtain lentivirus particles carrying the fusion imaging gene.
Public/Granted literature
Information query
