A computing system includes an array of configurable units made up of sub-arrays of configurable units. Each sub-array has a first number of configurable compute units and a second number of configurable memory units with a first spatial arrangement. Each configurable unit includes a configuration data store. The system also includes a statically configurable bus system coupled to the configurable units and a tag indicating a sub-array of configurable units having a defect. A defect-aware configuration controller sends configuration data to the configuration data stores to implement a data processing operation using the array of configurable units by generating static route control signals for the statically configurable bus system, based on the tag and without support of a host processor, to send a portion of the configuration data targeted to the sub-array having the defect to a configuration data store of an alternative sub-array of configurable units in the array.