To maximize throughput, an optimization method includes determining at least one precoding matrix and at least one combining matrix together according to Bayesian Optimization, Causal Bayesian Optimization, or Dynamic Causal Bayesian Optimization, and outputting the at least one precoding matrix and the at least one combining matrix. The at least one precoding matrix is configured for at least one precoder of a transmitter. The at least one combining matrix is configured for at least one combiner of at least one receiver.