Invention Grant
- Patent Title: Mutant CPF1 endonucleases
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Application No.: US15734839Application Date: 2019-06-04
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Publication No.: US12152257B2Publication Date: 2024-11-26
- Inventor: Stefano Stella , Guillermo Montoya
- Applicant: University of Copenhagen
- Applicant Address: DK Copenhagen K
- Assignee: University of Copenhagen
- Current Assignee: University of Copenhagen
- Current Assignee Address: DK Copenhagen K
- Agency: Steptoe LLP
- Agent Z. Ying Li; Debashree Chatterjee
- Priority: EP18175707 20180604,EP18190950 20180827
- International Application: PCT/EP2019/064444 WO 20190604
- International Announcement: WO2019/233990 WO 20191212
- Main IPC: C12N9/22
- IPC: C12N9/22 ; C12Q1/6806
Abstract:
The present invention relates to mutant Cpf1 endonucleases having altered activity compared to the wild type Cpf1, and their use to introduce single strand breaks in nucleic acid sequences. Methods for detection and quantification of a nucleic acid sequence are also disclosed. Methods for diagnosis of an infectious disease are also disclosed.
Public/Granted literature
- US20210230567A1 MUTANT CPF1 ENDONUCLEASES Public/Granted day:2021-07-29
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