DNA sequence modification-based gene drive

Invention Grant

US12157883B2 DNA sequence modification-based gene drive 有权

Patent Title: DNA sequence modification-based gene drive
Application No.: US15970728

Application Date: 2018-05-03
Publication No.: US12157883B2

Publication Date: 2024-12-03
Inventor: Bruce A Hay , Georg Oberhofer , Tobin William Ivy
Applicant: California Institute of Technology
Applicant Address: US CA Pasadena
Assignee: California Institute of Technology
Current Assignee: California Institute of Technology
Current Assignee Address: US CA Pasadena
Agency: Knobbe, Martens, Olson & Bear, LLP
Main IPC: C12N15/10
IPC: C12N15/10 ; C12N5/14 ; C12N5/16 ; C12N15/90 ; C12N15/74 ; C12N15/80 ; C12N15/82

Abstract:

Described herein are embodiments relating to manipulation of populations and sex ratio in populations through DNA sequence modifications.

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Espacenet

IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12N	微生物或酶；其组合物；繁殖、保藏或维持微生物；变异或遗传工程；培养基（微生物学的试验介质入C12Q1/00）。
C12N15/00	突变或遗传工程；遗传工程涉及的DNA或RNA，载体（如质粒）或其分离、制备或纯化；所使用的宿主（突变体或遗传工程制备的微生物本身入C12N1/00、C12N5/00、C12N7/00；新的植物入A01H；用组织培养技术再生植物入A01H4/00；新的动物入A01K67/00；含有插入活体细胞的遗传物质以治疗遗传疾病的药剂的应用，基因疗法入A61K48/00，一般肽入C07K）
C12N15/09	.DNA重组技术
C12N15/10	..分离、制备或纯化DNA或RNA的方法（DNA或RNA的化学制备入C07H21/00；自微生物中或用酶制备非结构多核苷酸入C12P19/34）