- Patent Title: Proteins for the treatment of epithelial barrier function disorders
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Application No.: US18354372Application Date: 2023-07-18
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Publication No.: US12168677B2Publication Date: 2024-12-17
- Inventor: Andrew Wonhee Han , Andrew W. Goodyear , Tarunmeet Gujral , Todd Zachary DeSantis , Karim Dabbagh
- Applicant: Genevive, Inc.
- Applicant Address: US CA San Mateo
- Assignee: Genevive, Inc.
- Current Assignee: Genevive, Inc.
- Current Assignee Address: US CA San Mateo
- Agency: Fish & Richardson P.C.
- Main IPC: C07K14/195
- IPC: C07K14/195 ; A61K38/16 ; A61K45/06 ; A61P1/04 ; C12N1/20 ; C12N5/07 ; C12N15/70 ; C12N15/85
Abstract:
The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.
Public/Granted literature
- US20240076323A1 PROTEINS FOR THE TREATMENT OF EPITHELIAL BARRIER FUNCTION DISORDERS Public/Granted day:2024-03-07
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