A method and apparatus for constructing a drug knowledge graph are provided. The method may include: identifying entities in a drug text; replacing medical key entities among the entities with character strings that conform to a preset rule, to obtain a replaced text; restoring the character strings in a word segmentation result, determined based on the replaced text, to the medical key entities replaced by the character strings; forming a linear entity relationship between the entities based on the entities; and generating a drug knowledge graph according to a parsing result obtained by syntactically parsing the linear entity relationship.