A memory interface circuitry includes a clock generator to convert the first clock signal into a second clock signal, a state machine to generate a test signal according to the second clock signal, a data pattern generator to generate a plurality of pre-defined data, a read register to sequentially output the plurality of pre-defined data, an I/O interface to capture a plurality of data from the plurality of pre-defined data according to a write strobe signal, a write register to receive and store the plurality of data from the I/O interface, and a comparator to compare the plurality of pre-defined data with the plurality of data to generate a test result. The test result is configured to verify an operation of the I/O interface.