A method of optimizing a RFID reader system to increase the percentage of RFID tags successfully inventoried in a container comprising a relatively large number of RFID tagged items in close proximity to one another. To achieve the greater percentage of successfully inventoried RFID tagged items, a transmitting system capable of reading an RFID tag and a receiving system capable of determining how much of the transmitted power propagates through the volume of RFID tagged items is positioned on either side of the container. A host system in communication with both the transmitting and receiving systems then utilizes one or more parameters of the transmitting system to maximize propagation of the RFID signal through the container and, therefore, increase the percentage of RFID tags successfully inventoried with the ultimate goal being 100%.