A system, method and apparatus to control memory devices over computer networks. For example, a server system establishes a secure authenticated connection with a client computer system. Over the connection, the server receives from the client computer system a request identifying a memory device and determine, based on data stored in the server system, that the client computer system is eligible to control the memory device. In response to a request from the client computer system, the server system generates a digital signature for a command using at least a cryptographic key stored in the server system in association with the memory device. The client computer system receives the digital signature from the server system and submits the command with the digital signature to the memory device. The memory device validates the digital signature prior to execution of the command.