A driver substrate and a display panel are disclosed. The driver substrate includes a base substrate and a flexible circuit board. The base substrate has a first bonding portion. The flexible circuit board is disposed on a bonding surface of the first bonding portion and bends from the bonding surface to a side of the first bonding portion away from the bonding surface. The flexible circuit board includes a bent portion, an anti-scratch structure is disposed between the bent portion and the first bonding portion, and the bent portion is attached to the anti-scratch structure.