In one embodiment, an access point is configured with a plurality of resource units (RUs). Each RU is configured to use a frequency range that differs from frequency ranges used by the other RUs. The access point determines a pattern of recurring signal performance over time. For each RU of the plurality of RUs, the pattern indicates the recurring signal performance with respect to a station when the station is located in a given physical location. The access point allocates one or more of the RUs for communicating with the station. The pattern is used for avoiding allocation of any of the RUs for which the station is predicted to experience strong multipath fading or other destructive interference.