A liquid crystal display panel drive method including: determining a target pixel in a picture of a (k+1)-th frame according to a grayscale data of the (k+1)-th frame; acquiring a number difference between positive polarities and negative polarities in polarities of data drive signals of target pixels in a same row in the picture of the (k+1)-th frame; adjusting, a polarity of a data drive signal of a target pixel of the target row in the (k+1)-th frame data drive signal, and making an absolute value of the number difference corresponding to the target row to be less than or equal to the preset number; and driving the liquid crystal display panel to display the picture of the (k+1)-th frame based on the (k+1)-th frame data drive signal after being adjusted.