Invention Application
US20030138847A1 Dosing form for a polymer support, use of said dosing form in organic chemical synthesis and method for production of said dosing form
审中-公开
用于聚合物载体的剂量形式,在有机化学合成中使用所述加料形式以及用于生产所述加料形式的方法
- Patent Title: Dosing form for a polymer support, use of said dosing form in organic chemical synthesis and method for production of said dosing form
- Patent Title (中): 用于聚合物载体的剂量形式,在有机化学合成中使用所述加料形式以及用于生产所述加料形式的方法
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Application No.: US10245839Application Date: 2002-09-16
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Publication No.: US20030138847A1Publication Date: 2003-07-24
- Inventor: Thomas Ruhland , Per Holm , Kirsten Schultz , Jannie Egeskov Holm , Kim Andersen
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby-Copenhagen
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby-Copenhagen
- Priority: DKPA200000450 20000317
- Main IPC: G01N033/53
- IPC: G01N033/53 ; C08G063/91 ; G01N033/543 ; C08G063/48

Abstract:
A dosing form for a polymer support for organic chemical synthesis in a solvent medium comprising a fixed weight amount of beads of a polymer containing functional groups, which polymer is insoluble in the solvent for the intended synthesis, is provided as compressed tablets of essentially equal weight and composition wherein the polymer beads are essentially intact and are released as such when the tablets are disintegrated in said solvent. Use of the dosing form is made in conventional synthesis, in parallel synthesis, in split and mix synthesis and/or combinatorial chemistry. In a method for producing the dosing form, beads of a polymer having functional gropusgroups is compressed into tablets after pre-treatment with an aprotic organic solvent groups are compressed into tablets after pre-treatment with an aprotic organic solvent.
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