A flexible diffuser membrane for diffusing gas into a liquid includes a substrate covered wholly or partially by a thin fluorocarbon elastomer coating. The coating is applied after the substrate has been fully constructed and cured. The coating is then mixed with an adhesive catalyst and applied by spraying or in another suitable manner to the substrate. The substrate and coating are then heated to a temperature such as 350° F.-800° F. adequate to form a strong chemical, molecular and adhesive bond between the coating and substrate. Perforations are formed in the membrane, the substrate may be treated with a biocide allowing the uncoated edges of the perforations to be coated with the biocide and resist biological growth.