Invention Application
US20120094308A1 KIT AND METHOD FOR THE PREMORTEM IN VITRO DETECTION OF ALZHEIMER'S DISEASE
审中-公开
用于ALZHEIMER病的血清检测中的前体试剂盒和方法
- Patent Title: KIT AND METHOD FOR THE PREMORTEM IN VITRO DETECTION OF ALZHEIMER'S DISEASE
- Patent Title (中): 用于ALZHEIMER病的血清检测中的前体试剂盒和方法
-
Application No.: US13377751Application Date: 2009-07-23
-
Publication No.: US20120094308A1Publication Date: 2012-04-19
- Inventor: Celia Sanchez Ramos
- Applicant: Celia Sanchez Ramos
- Applicant Address: ES Madrid
- Assignee: UNIVERSIDAD COMPLUTENSE DE MADRID
- Current Assignee: UNIVERSIDAD COMPLUTENSE DE MADRID
- Current Assignee Address: ES Madrid
- Priority: ESP20090001632 20090723
- International Application: PCT/ES09/00392 WO 20090723
- Main IPC: G01N21/64
- IPC: G01N21/64 ; G01N33/82 ; G01N33/566

Abstract:
Kit and method for the pre mortem in vitro detection of Alzheimer's disease The invention relates to a detection kit for Alzheimer's disease based on the vitro identification of the presence of biomarkers in the remains normally discarded after crystalline lens surgery. The kit can be used for the pre mortem detection of the disease, even before the appearance of clinical symptoms. Among the available biomarkers, the biomarker of choice is beta-amyloid peptide, for which several methods of sample processing and labelling for the presence of the biomarker may be used. Embodied in the invention is also the use of the crystalline lens remains discarded during surgery, often cataract surgery, to prepare a method for the in vitro pre mortem detection of Alzheimer's disease.
Information query