A compression therapy system for treating deep vein thrombosis in disclosed. The system provides sequential, graduated compression to a selected limb or body part. The system includes a portable compression device having multiple outlets. In one embodiment, up to three outputs may be selectively activated by a user. The wraps may be provided with cold therapy wraps. In a second embodiment, the system utilizes a timer to determine which, if any, of several wraps may be attached and inflates a detected wrap to a correct pressure or powers off the system as may be appropriate.