Invention Application
US20130281695A1 INTERMEDIATES OF SITAGLIPTIN AND PREPARATION PROCESS THEREOF
有权
SITAGLIPTIN的中间体及其制备方法
- Patent Title: INTERMEDIATES OF SITAGLIPTIN AND PREPARATION PROCESS THEREOF
- Patent Title (中): SITAGLIPTIN的中间体及其制备方法
-
Application No.: US13988261Application Date: 2011-12-01
-
Publication No.: US20130281695A1Publication Date: 2013-10-24
- Inventor: Xianhua Pan , Weijin Li , Qunhui Zhang , Libo Ruan , Wansheng Yu , Fei Deng , Tianhua Ma , Mingwang Huang , Minhuan He
- Applicant: Xianhua Pan , Weijin Li , Qunhui Zhang , Libo Ruan , Wansheng Yu , Fei Deng , Tianhua Ma , Mingwang Huang , Minhuan He
- Applicant Address: CN Taizhou, Zhejiang
- Assignee: ZHEJIANG HISOAR PHARMACEUTICAL CO., LTD.
- Current Assignee: ZHEJIANG HISOAR PHARMACEUTICAL CO., LTD.
- Current Assignee Address: CN Taizhou, Zhejiang
- Priority: CN201010579056.9 20101203
- International Application: PCT/CN2011/083315 WO 20111201
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D203/08 ; C07C319/20 ; C07F7/10 ; C07C323/25 ; C07D203/10 ; C07D203/24
Abstract:
Disclosed are intermediates of Sitagliptin, a preparation process thereof, and a process for synthesizing Sitagliptin using these intermediates. Sitagliptin is synthesized by using chiral amino compounds as a raw material, without having to build a chiral center with a chiral asymmetric catalytic hydrogenation, and high-pressure hydrogenation is avoided.
Public/Granted literature
- US09187419B2 Intermediates of sitagliptin and preparation process thereof Public/Granted day:2015-11-17
Information query
