Invention Application
US20130289249A1 SIMPLIFIED ONE-POT SYNTHESIS OF [18F]SFB FOR RADIOLABELING
有权
[18F] SFB用于放射性标签的简化单点合成
![SIMPLIFIED ONE-POT SYNTHESIS OF [18F]SFB FOR RADIOLABELING](/docs/US/2013-10-31/US20130289249A1/abs.jpg.600x600.jpg)
- Patent Title: SIMPLIFIED ONE-POT SYNTHESIS OF [18F]SFB FOR RADIOLABELING
- Patent Title (中): [18F] SFB用于放射性标签的简化单点合成
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Application No.: US13924397Application Date: 2013-06-21
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Publication No.: US20130289249A1Publication Date: 2013-10-31
- Inventor: Sebastian Olma , Clifton Kwang-Fu Shen
- Applicant: The Regents of the University of California
- Main IPC: C07K1/13
- IPC: C07K1/13 ; C07D207/46
![SIMPLIFIED ONE-POT SYNTHESIS OF [18F]SFB FOR RADIOLABELING](/abs-image/US/2013/10/31/US20130289249A1/abs.jpg.150x150.jpg)
Abstract:
A non-aqueous single pot synthesis of [18F]SFB is set forth. The [18F]SFB produced with this method is then used, for example, to label a peptide or an engineered antibody fragment (diabody) targeting human epidermal growth factor receptor 2 (HER2) as representative examples of labeled compounds for use as an injectable composition to locate abnormal tissue, specifically tumors within an animal or human using a PET scan.
Public/Granted literature
- US09096647B2 Simplified one-pot synthesis of [18F]SFB for radiolabeling Public/Granted day:2015-08-04
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