Generally described herein are methods and systems for enhanced tamper and malware resistant computer architectures. A system for enhanced tamper and malware resistance can include a harvardizer configured to receive comingled instructions and data and produce separated instructions and data. A data memory can be configured to receive the separated data. An instruction memory that is physically separate from the data memory can be configured to receive the separated instructions. The system can include one or more computer processors that can be configured to execute the separated instructions and data. The system can include one or more encryptors or decryptors to help thwart injection based attacks.