Invention Application
- Patent Title: BISPECIFIC HETERODIMERIC DIABODIES AND USES THEREOF
- Patent Title (中): 双相双极体双极体及其用途
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Application No.: US14751704Application Date: 2015-06-26
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Publication No.: US20160002357A1Publication Date: 2016-01-07
- Inventor: Chad Michael MAY , Adam Reid ROOT , William A. BRADY , Lioudmila Gennadievna TCHISTIAKOVA , Lidia MOSYAK , Laird BLOOM , Paul A. MOORE , Leslie S. JOHNSON
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: PFIZER INC.
- Current Assignee: PFIZER INC.
- Current Assignee Address: US NY New York
- Main IPC: C07K16/46
- IPC: C07K16/46 ; C07K16/28 ; C07K16/18
Abstract:
Bispecific heterodimeric diabody molecules and uses thereof in the treatment of cancer. The bispecific heterodimeric diabody molecules comprise two polypeptide chains that associate to form two epitope binding sites recognizing the P-cadherin tumor cell associated antigen and the CD3 T cell antigen.
Public/Granted literature
- US09884921B2 Bispecific heterodimeric diabodies and uses thereof Public/Granted day:2018-02-06
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