Invention Application
US20160208088A1 Racemic Drug Resolution Using Polymer Supported Chiral Selector
有权
使用聚合物支持手性选择剂的外消旋药物分辨率
- Patent Title: Racemic Drug Resolution Using Polymer Supported Chiral Selector
- Patent Title (中): 使用聚合物支持手性选择剂的外消旋药物分辨率
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Application No.: US14915326Application Date: 2014-09-01
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Publication No.: US20160208088A1Publication Date: 2016-07-21
- Inventor: Sachin Tanaji Mane , Siona Virgil Daniels , Sarika Babasaheb Deokar , Smita Atmaran Mule , Surendra Ponrathnam , Nayaku Nivrati Chavan
- Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEAECH
- Priority: IN2570/DEL/2013 20130830
- International Application: PCT/IN2014/000561 WO 20140901
- Main IPC: C08L33/14
- IPC: C08L33/14 ; B01J20/22 ; B01J20/281 ; B01J20/26 ; C08L33/12 ; C08L47/00
Abstract:
The present invention relates to a process for the separation of enantiomers or resolution of racemic mixtures using high surface area core-shell polymer beads. The present invention further relates to a core-shell functionalized polymer comprising a core which comprises copolymer made from monomers selected from non-aromatic acrylate, ethylene dimethacrylate and divinyl-benzene, a shell which comprises monomers selected from glycidyl ethers of methacrylate and a chiral selector selected from tartaric acid derivatives and amino acids.
Public/Granted literature
- US09809706B2 Racemic drug resolution using polymer supported chiral selector Public/Granted day:2017-11-07
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