An information processing system includes a communication control device that receives an input of first process communication from a first information processing device and controls internal and external communication with a second information processing device, and a responding device that can communicate with the communication control device, wherein upon receiving the first process communication, the communication control device transmits the received first process communication to the second information processing device, and upon receiving second process communication, which is a response to the first process communication transmitted from the second information processing device to the first information processing device, the communication control device transmits the second process communication to the responding device by changing a destination of the second process communication from the first information processing device to the responding device.