Invention Application
US20160348086A1 Improved Carbon Dioxide Fixation Via Bypassing Feedback Regulation
审中-公开
通过旁路反馈调节改进二氧化碳固定
- Patent Title: Improved Carbon Dioxide Fixation Via Bypassing Feedback Regulation
- Patent Title (中): 通过旁路反馈调节改进二氧化碳固定
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Application No.: US15115670Application Date: 2015-01-30
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Publication No.: US20160348086A1Publication Date: 2016-12-01
- Inventor: Yi-Xin Huo , Benjamin Schilling , Shahrooz Rabizadeh
- Applicant: EASEL BIOTECHNOLOGIES, LLC
- Applicant Address: US CA Culver City
- Assignee: Easel Biotechnologies, LLC
- Current Assignee: Easel Biotechnologies, LLC
- Current Assignee Address: US CA Culver City
- International Application: PCT/US2015/013947 WO 20150130
- Main IPC: C12N9/88
- IPC: C12N9/88 ; C12P5/02 ; C12N15/74 ; C12N9/12 ; C10L1/00 ; C12P7/16

Abstract:
Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.
Public/Granted literature
- US10113160B2 Carbon dioxide fixation via bypassing feedback regulation Public/Granted day:2018-10-30
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