A system for efficiently filling liquid containing bottles having removable and replaceable threaded screw tops. The system includes a bottle spindle mechanism having a bottle receiving receptacle, and a liquid dispensing head movable between a raised position for enabling placement and removal of bottles into and from the receptacle with the screw tops in place and lowered liquid dispensing position. With a bottle in the receptacle, the receptacle and bottle are rotatable in one rotary direction while the screw top is manually retained against rotation for unscrewing and removing the screw top; the dispensing head is then lowered to the liquid dispensing position for filling the bottle; the dispensing head then is raised and the screw top repositioned on the bottle; and the receptacle and bottle are rotated in an opposite direction while the screw top is retained for rescrewing the screw top on the bottle.