A plastic film is produced by blending a polymer with particles encapsulating an oxidizing agent, such as hydrogen peroxide. Optionally, an “oxodegradable” and/or “oxo biodegradable” additive that promotes degradation of the polymer in the presence of oxygen may be blended into the plastic film. The presence of the oxidizing agent within the plastic film ensures degradation of an article of manufacture, e.g., a plastic bag, when it is disposed of in an anaerobic environment, such as a landfill. In some embodiments, the particles are microcapsules and/or nanocapsules each having a polymer shell encapsulating a core that includes the oxidizing agent. In some embodiments, the particles are microparticles and/or nanoparticles each having a matrix in which the oxidizing agent is encapsulated.