Disclosed is a self-test device and method for assessing the functional performance of a reader device that is configured to interface with a wireless sensor. The self-test device may be configured to analyze the accuracy of a signal transmitted from the reader device or the accuracy of a signal received by the reader device. In one embodiment, the reader device may be configured to engage the self-test device to allow the reader to transmit a signal, such as a short pulse of energy or a short burst of radio frequency energy to cause the self-test device to output a resonant signal. The self-test device may receive the transmit signal from the reader and evaluate it against predetermined values. The evaluated signals may be used to assess the accuracy of the transmit signal of the reader device to identify potential calibration issues and initiate remedial action by an automated system or human intervention if needed. The self-test device may be built into a docking station where the reader is placed when not in use.