Invention Application
- Patent Title: KRAS G12C INHIBITORS
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Application No.: US16191190Application Date: 2018-11-14
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Publication No.: US20190144444A1Publication Date: 2019-05-16
- Inventor: James F. Blake , Laurence E. Burgess , Mark Joseph Chicarelli , James Gail Christensen , Adam Cook , Jay Bradford Fell , John P. Fischer , Matthew Arnold Marx , Macedonio J. Mejia , Pavel Savechenkov , Guy P.A. Vigers , Christopher Ronald Smith , Martha E. Rodriguez
- Applicant: Mirati Therapeutics, Inc. , Array BioPharma Inc.
- Assignee: Mirati Therapeutics, Inc.,Array BioPharma Inc.
- Current Assignee: Mirati Therapeutics, Inc.,Array BioPharma Inc.
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D491/08 ; A61P35/00
Abstract:
The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
Public/Granted literature
- US10689377B2 KRas G12C inhibitors Public/Granted day:2020-06-23
Information query
