A system for reducing noise in a camera image is disclosed. The system includes one or more processors, and a camera operatively coupled to the processor, the processors are configured to reduce noise of camera images, the processors are configured to receive input image data from the camera representing pixel data from a plurality of pixels, segment the input image data to a plurality of segments and for each segment establish an initial segment image, pre-correct pixel data by modifying the pixel data to account for voltage offset and gain of each pixel based on a predetermined map of gain and offset, and obtain an estimate of an output image by minimizing a cost function and output and stitch the estimated image to other estimated and outputted image segments, and output a noise reduced image including the stitched estimated images.