A low-delay hybrid noise reduction system includes a reference audio receiving device, an error audio receiving device, an audio output device, and an audio processing device. The audio processing device includes a feedforward noise reduction filter module, a feedback noise reduction filter module, and a mixer. The feedforward noise reduction filter module includes a feedforward least mean squares (LMS) filter, a low-stage finite impulse response (FIR) filter, and 1st to Nth-stage biquad filters. The 1st to Nth-stage biquad filters is set on the input end of the low-stage finite impulse response filter to perform low-delay filtering on the reference source audio signal received and outputs to the low-stage FIR filter so as to output the feedforward noise reduction signal through the low-stage FIR filter.