Methods and systems are provided for regenerating an after-treatment system of a vehicle. A first operational parameter of a first component of the after-treatment system is monitored and a second operational parameter, different to the first operational parameter, of a second component of the after-treatment system is monitored. It is determined if the first operational parameter of the first component is outside a first threshold range and if the second operational parameter is approaching a second threshold and, in response to the first operational parameter being outside the first threshold range and the second operational parameter being within the second threshold range, a regeneration sequence of the after-treatment system configured to regenerate at least the first component of the after-treatment system is initiated.