Particular embodiments described herein provide for a system and method for facilitating autonomous delivery using a delivery assembly transported by an autonomous vehicle, the system and method can include determining a location of the delivery assembly and in response to determining the location of the delivery assembly, configuring a user interface to facilitate the autonomous delivery. The user interface has at least a point of origination configuration and a user configuration. In addition, the user interface can authenticate a user, allow the user to access one or more cubbies of the delivery assembly, and inform the user through one or more indicators on the user interface that the user can access a specific cubby.