Various implementations include audio devices and methods for noise reduction control in wearable audio devices and/or vehicle audio systems. Certain implementations include a non-occluding wearable audio device having: at least one electro-acoustic transducer; at least one microphone; and a control system coupled with the at least one electro-acoustic transducer and the at least one microphone, the control system programmed to: adjust an active noise reduction (ANR) setting for audio output to the at least one electro-acoustic transducer in response to detecting use of the non-occluding wearable audio device in a vehicle.