A high-voltage module, such as a traction battery, a traction inverter, or a DC/DC converter of a traction powertrain of an electrified vehicle (EV), includes an enclosure and a fuse box. An electronics assembly for performing electrical power operations is housed within the enclosure. The enclosure has a socket. The fuse box is removably insertable into the socket of the enclosure. The fuse box connects to the electronics assembly while the fuse box is inserted into the socket of the enclosure for the fuse box to provide a power distribution and fuse protection arrangement to the electronics assembly.