Devices for active athermalization and lens position indexing include an image capture device that includes a lens assembly, a lens mount, a memory, a printed circuit board (PCB), an image sensor, a temperature sensor, and actuator, and a processor. The memory stores a calibration look up table (LUT) that includes focus positions across a temperature range. The image sensor may be disposed on the PCB. The temperature sensor measures a temperature of the lens assembly. The processor determines a position of the lens assembly relative to the image sensor to maintain a focus point over the temperature range based on the calibration LUT, the measured temperature, or both. The processor may be configured to transmit a control signal to the actuator to modify the position of the lens assembly relative to the image sensor to maintain the focus point based on the measured temperature.