A fluid delivery system is disclosed which includes a pump and a fluid delivery set. The fluid delivery set includes a stop cock valve, and the pump includes a valve actuation unit into which the stop cock valve is positioned for operation of the system. The valve actuation unit includes a valve receiving mechanism which requires the valve to be closed in order to be inserted into or removed from the valve actuation unit, thereby preventing accidental free flow of fluid at all times. The fluid delivery set may also include an auxiliary fluid source to allow periodic flushing of the fluid delivery line, and the valve actuation unit can be programmed by the pump to automatically initiate periodic flushing cycles if desired.