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US06518048B2 Stereo-specific synthesis of shimikic acid derivatives with improved efficiency 有权
具有提高效率的视黄酸衍生物的立体特异性合成

  • Patent Title: Stereo-specific synthesis of shimikic acid derivatives with improved efficiency
  • Patent Title (中): 具有提高效率的视黄酸衍生物的立体特异性合成
  • Application No.: US09811862
    Application Date: 2001-03-19
  • Publication No.: US06518048B2
    Publication Date: 2003-02-11
  • Inventor: Hans Iding , Beat Wirz , Ulrich Zutter
  • Applicant: Hans Iding , Beat Wirz , Ulrich Zutter
  • Priority: EP00107669 20000410
  • Main IPC: C12P1300
  • IPC: C12P1300
Stereo-specific synthesis of shimikic acid derivatives with improved efficiency
Abstract:
The invention provides a multistep synthesis for the preparation of 4,5-diamino shikimic acid derivatives of formula starting from an isophthalic acid derivative of formula 4,5-Diamino shikimic acid derivatives are potent inhibitors of viral neuraminidase.
Abstract(Chinese):

本发明提供了一种用于制备由式4,5间二苯二甲酸衍生物配制的4,5-二氨基莽草酸衍生物的多步合成。二氨基莽草酸衍生物是病毒神经氨酸酶的有效抑制剂。

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