Invention Grant
- Patent Title: Alpha 1-antitrypsin preparation as well as a method for producing the same
- Patent Title (中): α1-抗胰蛋白酶制剂及其制备方法
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Application No.: US09963341Application Date: 2001-09-24
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Publication No.: US06974792B2Publication Date: 2005-12-13
- Inventor: Erwin Mattes , H. Peter Matthiessen
- Applicant: Erwin Mattes , H. Peter Matthiessen
- Applicant Address: AU Vienna
- Assignee: Baxter Aktiengesellschaft
- Current Assignee: Baxter Aktiengesellschaft
- Current Assignee Address: AU Vienna
- Agent Patrick S. Eagleman
- Priority: AT1007/97 19970610
- Main IPC: A61K38/55
- IPC: A61K38/55 ; A61K38/00 ; A61P1/16 ; A61P11/00 ; A61P43/00 ; C07K1/16 ; C07K14/81 ; C12N7/04 ; C12N9/50
Abstract:
A native, chromatographically purified α1-AT preparation having a purity of at least 0.7 PU/mg protein and a relative plasma α1-AT activity of at least 120% is disclosed. The ratio of active to inactive α1-AT is higher than in plasma.Furthermore, a method of producing this preparation is disclosed, as well as the use of a carrier material, e.g. an inorganic carrier material such as hydroxylapatite for separating active α1-AT from inactive α1-AT.
Public/Granted literature
- US20020082214A1 Alpha 1-antitrypsin preparation as well as a method for producing the same Public/Granted day:2002-06-27
Information query
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