To overcome problems of fabricating conventional core-clad optical fibre from non-silica based (compound) glass, it is proposed to fabricate non-silica based (compound) glass optical fibre as holey fibre i.e. one contining Longitudinal holes in the cladding. This removes the conventional problems associated with mismatch of the physical properties of the core and clad compound glasses, since a holey fibre can be made of a single glass composition. With a holey fibre, it is not necessary to have different glasses for the core and cladding, since the necessary refractive index modulation between core and cladding is provided by the microstructure of the clad, i.e. its holes, rather than by a difference in materials properties between the clad and core glasses. Specifically, the conventional thermal mismatch problems between core and clad are circumvented. A variety of fibre types can be fabricated from non-silica based (compounds) glasses, for example: single-mode fibre; photonic band gap fibre; highly non-linear fibre; fibre with photosensitivity written gratings and other refractive index profile structures; and rare-earth doped fibres (e.g. Er, Nd, Pr) to provide gain media for fibre amplifiers and lasers.