A signal transmission cable with adaptive contact pin reference structure includes a first cable having a connecting edge; a second cable having a connecting edge; a component lay-out section having a first lateral edge adjacent to the connecting edge of the first cable, and a second lateral edge; and an overlapping section having an inner lateral edge adjacent to the second lateral edge of said component lay-out section with a folding line formed between them, and an outer lateral edge adjacent to the connecting edge of the second cable with another folding line formed between them. Signal transmission lines included in the component lay-out section and the first cable are correspondingly connected with one another, and signal transmission lines included in the overlapping section are correspondingly connected to those included in the second cable and the component lay-out section.