Invention Grant
- Patent Title: Copper-catalysed ligation of azides and acetylenes
- Patent Title (中): 铜催化的叠氮化物和乙炔的连接
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Application No.: US10516671Application Date: 2003-05-30
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Publication No.: US07375234B2Publication Date: 2008-05-20
- Inventor: K. Barry Sharpless , Valery Fokin , Vsevold A. Rostovtsev , Luke Green , Fahmi Himo
- Applicant: K. Barry Sharpless , Valery Fokin , Vsevold A. Rostovtsev , Luke Green , Fahmi Himo
- Applicant Address: US CA La Jolla
- Assignee: The Scripps Research Institute
- Current Assignee: The Scripps Research Institute
- Current Assignee Address: US CA La Jolla
- Agent Donald G. Lewis; Talivaldis Cepuritis; Thomas Fitting
- International Application: PCT/US03/17311 WO 20030530
- International Announcement: WO03/101972 WO 20031211
- Main IPC: C07D249/04
- IPC: C07D249/04 ; C07D249/06 ; C07D403/06 ; C07D403/14
Abstract:
A metal catalyzed click chemistry ligation process is employed to bind azides and terminal acetylenes to give triazoles. In many instances, the reaction sequence regiospecifically ligates azides and terminal acetylenes to give only 1,4-disubstituted [1,2,3]-triazoles.
Public/Granted literature
- US20050222427A1 Copper-catalysed ligation of azides and acetylenes Public/Granted day:2005-10-06
Information query
