Invention Grant
US07501241B2 Method of transcribing biomolecular patterns, method of manufacturing chip boards, and method of manufacturing biochips 失效
转录生物分子模式的方法,制造芯片板的方法以及制造生物芯片的方法

Method of transcribing biomolecular patterns, method of manufacturing chip boards, and method of manufacturing biochips
Abstract:
A method of mass-producing minute structures such as biochips, protein chips, quantum dots, and quantum chips involves arranging an antigen two-dimensionally on a board and arranging probes two-dimensionally facing the same direction so that the binding sites of the probes may bind to the antigen. An inorganic substance such as Ni is deposited on the board from the upper side of the probes by sputtering or evaporation to form a thin film layer and on the top surface of the flatly formed thin film layer, a supporting layer is formed by separating out the same inorganic substance using electrotyping. Then, by peeling the thin film layer and the supporting layer off of the board together, the mother stamper having cavities for the patterns of biomolecules is obtained.
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