A non-pneumatic clamp and drilling system with a cabinet having a work surface with a drill bit opening. A fence rests on the work surface to guide a side surface of a workpiece. A clamp is secured to the cabinet. The clamp includes clamp pad positioned above the work surface. A drill with a collet is movably secured to the cabinet beneath and at an acute angle to the work surface. The collet can hold a drill bit such that the longitudinal axis of the drill bit is parallel to the acute angle. A handle is operatively coupled to the clamp and the drill to simultaneously move the drill collet along the longitudinal axis and move the clamp pad. By manually moving the handle, the workpiece can be secured by the clamp pad and fence when the drill collet moves toward the drill bit opening in the work surface.