Invention Grant
- Patent Title: Beta-2-glycoprotein 1 is an inhibitor of angiogenesis
- Patent Title (中): β-2-糖蛋白1是血管发生的抑制剂
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Application No.: US11810521Application Date: 2007-06-05
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Publication No.: US07642234B2Publication Date: 2010-01-05
- Inventor: Alan Jay Schroit , Krishnakumar Balasubramanian , Marya F. McCarty
- Applicant: Alan Jay Schroit , Krishnakumar Balasubramanian , Marya F. McCarty
- Applicant Address: US TX Austin
- Assignee: Board of Regents The University of Texas Systems
- Current Assignee: Board of Regents The University of Texas Systems
- Current Assignee Address: US TX Austin
- Agency: Vinson & Elkins L.L.P.
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The present disclosure provides a method of inhibiting angiogenesis within a tissue of interest by providing either intact or nicked β-Glycoprotein 1 (β2GP1) to cells associated with the tissue. The presence of β2GP1 inhibits angiogenesis within the tissue, in part by preventing neovascularization into the tissue. The disclosure also provides a method for treating tumors by providing β2GP1 to the tumor.
Public/Granted literature
- US20080131397A1 Beta-2-glycoprotein 1 is an inhibitor of angiogenesis Public/Granted day:2008-06-05
Information query
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