Invention Grant
US07642285B2 Compounds and methods for modulating communication and virulence in quorum sensing bacteria
有权
用于调节群体感染细菌中的通讯和毒力的化合物和方法
- Patent Title: Compounds and methods for modulating communication and virulence in quorum sensing bacteria
- Patent Title (中): 用于调节群体感染细菌中的通讯和毒力的化合物和方法
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Application No.: US11275896Application Date: 2006-02-02
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Publication No.: US07642285B2Publication Date: 2010-01-05
- Inventor: Helen E. Blackwell , Grant D. Geske , Rachel W. Wezeman
- Applicant: Helen E. Blackwell , Grant D. Geske , Rachel W. Wezeman
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: Greenlee, Winner and Sullivan, P.C.
- Main IPC: A01N43/08
- IPC: A01N43/08 ; C07D309/30
Abstract:
The present invention provides compositions and methods for modulating the communication and virulence of quorum sensing bacteria. In various exemplary embodiments, the invention provides a combinatorial library of quorum sensing compounds including synthetic analogs of naturally occurring and non-naturally occurring acyl-homoserine lactone (AHL) analogs, and methods of synthesizing and using these compounds.
Public/Granted literature
- US20060178430A1 COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA Public/Granted day:2006-08-10
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