A fuel cell includes a removable and replaceable fuel supply having fuel disposed therein. A system for monitoring various parameters of the fuel such as temperature, pressure, and the levels of dissolved oxygen is provided. A plurality of sensors is disposed on the fuel supply side that is capable of communicating with a controller and memory on the fuel cell side. In another embodiment, at least one sensor for measuring a system parameter of the fuel communicates with an RFID tag either remotely or via a hardwired link. The sensor and/or the RFID tag may be coated with a substance impervious to the caustic fuel. An RFID reader station collects the data. The controller may be included to use the data in real time to alter system parameters, such as fuel pumping rates or a bleed off, or to trigger a signal, such as to notify a user of an empty fuel supply.